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Nitrate Respiration Protects Hypoxic Mycobacterium tuberculosis Against Acid- and Reactive Nitrogen Species Stresses

There are strong evidences that Mycobacterium tuberculosis survives in a non-replicating state in the absence of oxygen in closed lesions and granuloma in vivo. In addition, M. tuberculosis is acid-resistant, allowing mycobacteria to survive in acidic, inflamed lesions. The ability of M. tuberculosi...

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Detalles Bibliográficos
Autores principales: Tan, Mai Ping, Sequeira, Patricia, Lin, Wen Wei, Phong, Wai Yee, Cliff, Penelope, Ng, Seow Hwee, Lee, Boon Heng, Camacho, Luis, Schnappinger, Dirk, Ehrt, Sabine, Dick, Thomas, Pethe, Kevin, Alonso, Sylvie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965054/
https://www.ncbi.nlm.nih.gov/pubmed/21048946
http://dx.doi.org/10.1371/journal.pone.0013356