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Tamoxifen-Independent Recombination in the RIP-CreER Mouse

BACKGROUND: The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen recepto...

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Detalles Bibliográficos
Autores principales: Liu, Yanmei, Suckale, Jakob, Masjkur, Jimmy, Magro, Maria Grazia, Steffen, Anja, Anastassiadis, Konstantinos, Solimena, Michele
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965077/
https://www.ncbi.nlm.nih.gov/pubmed/21063464
http://dx.doi.org/10.1371/journal.pone.0013533