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Tamoxifen-Independent Recombination in the RIP-CreER Mouse
BACKGROUND: The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen recepto...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965077/ https://www.ncbi.nlm.nih.gov/pubmed/21063464 http://dx.doi.org/10.1371/journal.pone.0013533 |