Muscle Wasting and Impaired Myogenesis in Tumor Bearing Mice Are Prevented by ERK Inhibition

BACKGROUND: The onset of cachexia is a frequent feature in cancer patients. Prominent characteristic of this syndrome is the loss of body and muscle weight, this latter being mainly supported by increased protein breakdown rates. While the signaling pathways dependent on IGF-1 or myostatin were caus...

Descripción completa

Detalles Bibliográficos
Autores principales: Penna, Fabio, Costamagna, Domiziana, Fanzani, Alessandro, Bonelli, Gabriella, Baccino, Francesco M., Costelli, Paola
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965098/
https://www.ncbi.nlm.nih.gov/pubmed/21048967
http://dx.doi.org/10.1371/journal.pone.0013604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965098/
https://www.ncbi.nlm.nih.gov/pubmed/21048967
http://dx.doi.org/10.1371/journal.pone.0013604

Ejemplares similares