Regulators of the Proteasome Pathway, Uch37 and Rpn13, Play Distinct Roles in Mouse Development

Rpn13 is a novel mammalian proteasomal receptor that has recently been identified as an amplification target in ovarian cancer. It can interact with ubiquitin and activate the deubiquitinating enzyme Uch37 at the 26S proteasome. Since neither Rpn13 nor Uch37 is an integral proteasomal subunit, we ex...

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Detalles Bibliográficos
Autores principales: Al-Shami, Amin, Jhaver, Kanchan G., Vogel, Peter, Wilkins, Carrie, Humphries, Juliane, Davis, John J., Xu, Nianhua, Potter, David G., Gerhardt, Brenda, Mullinax, Robert, Shirley, Cynthia R., Anderson, Stephen J., Oravecz, Tamas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965108/
https://www.ncbi.nlm.nih.gov/pubmed/21048919
http://dx.doi.org/10.1371/journal.pone.0013654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965108/
https://www.ncbi.nlm.nih.gov/pubmed/21048919
http://dx.doi.org/10.1371/journal.pone.0013654

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