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Regulators of the Proteasome Pathway, Uch37 and Rpn13, Play Distinct Roles in Mouse Development
Rpn13 is a novel mammalian proteasomal receptor that has recently been identified as an amplification target in ovarian cancer. It can interact with ubiquitin and activate the deubiquitinating enzyme Uch37 at the 26S proteasome. Since neither Rpn13 nor Uch37 is an integral proteasomal subunit, we ex...
Autores principales: | Al-Shami, Amin, Jhaver, Kanchan G., Vogel, Peter, Wilkins, Carrie, Humphries, Juliane, Davis, John J., Xu, Nianhua, Potter, David G., Gerhardt, Brenda, Mullinax, Robert, Shirley, Cynthia R., Anderson, Stephen J., Oravecz, Tamas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965108/ https://www.ncbi.nlm.nih.gov/pubmed/21048919 http://dx.doi.org/10.1371/journal.pone.0013654 |
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