Histopathology and biochemistry analysis of the interaction between sunitinib and paracetamol in mice

BACKGROUND: Sunitinib, a tyrosine kinase inhibitor to treat GIST and mRCC may interact with paracetamol as both undergo P450 mediated biotransformation and P-glycoprotein transport. This study evaluates the effects of sunitinib-paracetamol coadministration on liver and renal function biomarkers and...

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Detalles Bibliográficos
Autores principales: Lim, Adeline YL, Segarra, Ignacio, Chakravarthi, Srikumar, Akram, Sufyan, Judson, John P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965131/
https://www.ncbi.nlm.nih.gov/pubmed/20950441
http://dx.doi.org/10.1186/1471-2210-10-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965131/
https://www.ncbi.nlm.nih.gov/pubmed/20950441
http://dx.doi.org/10.1186/1471-2210-10-14

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