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Antiangiogenic Activity of 2-Deoxy-D-Glucose

BACKGROUND: During tumor angiogenesis, endothelial cells (ECs) are engaged in a number of energy consuming biological processes, such as proliferation, migration, and capillary formation. Since glucose uptake and metabolism are increased to meet this energy need, the effects of the glycolytic inhibi...

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Detalles Bibliográficos
Autores principales: Merchan, Jaime R., Kovács, Krisztina, Railsback, Jaclyn W., Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G., Lehrman, Mark A., Lampidis, Theodore J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965179/
https://www.ncbi.nlm.nih.gov/pubmed/21060881
http://dx.doi.org/10.1371/journal.pone.0013699