The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis

The plasmid pRN1 encodes for a multifunctional replication protein with primase, DNA polymerase and helicase activity. The minimal region required for primase activity encompasses amino-acid residues 40–370. While the N-terminal part of that minimal region (residues 47–247) folds into the prim/pol d...

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Detalles Bibliográficos
Autores principales: Beck, Kirsten, Vannini, Alessandro, Cramer, Patrick, Lipps, Georg
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965215/
https://www.ncbi.nlm.nih.gov/pubmed/20511586
http://dx.doi.org/10.1093/nar/gkq447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965215/
https://www.ncbi.nlm.nih.gov/pubmed/20511586
http://dx.doi.org/10.1093/nar/gkq447

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