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New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA

Two archaeal tRNA methyltransferases belonging to the SPOUT superfamily and displaying unexpected activities are identified. These enzymes are orthologous to the yeast Trm10p methyltransferase, which catalyses the formation of 1-methylguanosine at position 9 of tRNA. In contrast, the Trm10p ortholog...

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Detalles Bibliográficos
Autores principales: Kempenaers, Morgane, Roovers, Martine, Oudjama, Yamina, Tkaczuk, Karolina L., Bujnicki, Janusz M., Droogmans, Louis
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965216/
https://www.ncbi.nlm.nih.gov/pubmed/20525789
http://dx.doi.org/10.1093/nar/gkq451