The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression

The control of messenger RNA (mRNA) function by micro RNAs (miRNAs) in animal cells requires the GW182 protein. GW182 is recruited to the miRNA repression complex via interaction with Argonaute protein, and functions downstream to repress protein synthesis. Interaction with Argonaute is mediated by...

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Detalles Bibliográficos
Autores principales: Chekulaeva, Marina, Parker, Roy, Filipowicz, Witold
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965232/
https://www.ncbi.nlm.nih.gov/pubmed/20530530
http://dx.doi.org/10.1093/nar/gkq501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965232/
https://www.ncbi.nlm.nih.gov/pubmed/20530530
http://dx.doi.org/10.1093/nar/gkq501

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