The crystal structure of an ‘All Locked’ nucleic acid duplex

‘Locked nucleic acids’ (LNAs) are known to introduce enhanced bio- and thermostability into natural nucleic acids rendering them powerful tools for diagnostic and therapeutic applications. We present the 1.9 Å X-ray structure of an ‘all LNA’ duplex containing exclusively modified β-d-2′-O-4′C-methyl...

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Detalles Bibliográficos
Autores principales: Eichert, André, Behling, Katja, Betzel, Christian, Erdmann, Volker A., Fürste, Jens P., Förster, Charlotte
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965234/
https://www.ncbi.nlm.nih.gov/pubmed/20530536
http://dx.doi.org/10.1093/nar/gkq505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965234/
https://www.ncbi.nlm.nih.gov/pubmed/20530536
http://dx.doi.org/10.1093/nar/gkq505

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