Reliable semi-synthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications

The 3′-peptidyl-tRNA conjugates that possess a hydrolysis-resistant ribose-3′-amide linkage instead of the natural ester linkage would represent valuable substrates for ribosomal studies. Up to date, access to these derivatives is severely limited. Here, we present a novel approach for the reliable...

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Detalles Bibliográficos
Autores principales: Graber, Dagmar, Moroder, Holger, Steger, Jessica, Trappl, Krista, Polacek, Norbert, Micura, Ronald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965236/
https://www.ncbi.nlm.nih.gov/pubmed/20525967
http://dx.doi.org/10.1093/nar/gkq508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965236/
https://www.ncbi.nlm.nih.gov/pubmed/20525967
http://dx.doi.org/10.1093/nar/gkq508

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