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Reliable semi-synthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications
The 3′-peptidyl-tRNA conjugates that possess a hydrolysis-resistant ribose-3′-amide linkage instead of the natural ester linkage would represent valuable substrates for ribosomal studies. Up to date, access to these derivatives is severely limited. Here, we present a novel approach for the reliable...
Autores principales: | Graber, Dagmar, Moroder, Holger, Steger, Jessica, Trappl, Krista, Polacek, Norbert, Micura, Ronald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965236/ https://www.ncbi.nlm.nih.gov/pubmed/20525967 http://dx.doi.org/10.1093/nar/gkq508 |
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