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Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter

Previous studies have demonstrated that nuclease hypersensitivity regions of several proto-oncogenic DNA promoters, situated upstream of transcription start sites, contain guanine-rich tracts that form intramolecular G-quadruplexes stabilized by stacked G•G•G•G tetrads in monovalent cation solution....

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Detalles Bibliográficos
Autores principales: Kuryavyi, Vitaly, Phan, Anh Tuân, Patel, Dinshaw J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965254/
https://www.ncbi.nlm.nih.gov/pubmed/20566478
http://dx.doi.org/10.1093/nar/gkq558