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Rat traps: filling the toolbox for manipulating the rat genome

The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities...

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Detalles Bibliográficos
Autores principales: van Boxtel, Ruben, Cuppen, Edwin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965381/
https://www.ncbi.nlm.nih.gov/pubmed/20887642
http://dx.doi.org/10.1186/gb-2010-11-9-217