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N-terminal and C-terminal heparin-binding domain polypeptides derived from fibronectin reduce adhesion and invasion of liver cancer cells

BACKGROUND: Fibronectin (FN) is known to be a large multifunction glycoprotein with binding sites for many substances, including N-terminal and C-terminal heparin-binding domains. We investigated the effects of highly purified rhFNHN29 and rhFNHC36 polypeptides originally cloned from the two heparin...

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Detalles Bibliográficos
Autores principales: Tang, Nan-Hong, Chen, Yan-Lin, Wang, Xiao-Qian, Li, Xiu-Jin, Wu, Yong, Zou, Qi-Lian, Chen, Yuan-Zhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965728/
https://www.ncbi.nlm.nih.gov/pubmed/20939933
http://dx.doi.org/10.1186/1471-2407-10-552