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N-terminal and C-terminal heparin-binding domain polypeptides derived from fibronectin reduce adhesion and invasion of liver cancer cells
BACKGROUND: Fibronectin (FN) is known to be a large multifunction glycoprotein with binding sites for many substances, including N-terminal and C-terminal heparin-binding domains. We investigated the effects of highly purified rhFNHN29 and rhFNHC36 polypeptides originally cloned from the two heparin...
Autores principales: | Tang, Nan-Hong, Chen, Yan-Lin, Wang, Xiao-Qian, Li, Xiu-Jin, Wu, Yong, Zou, Qi-Lian, Chen, Yuan-Zhong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965728/ https://www.ncbi.nlm.nih.gov/pubmed/20939933 http://dx.doi.org/10.1186/1471-2407-10-552 |
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