An Automated Phenotype-Driven Approach (GeneForce) for Refining Metabolic and Regulatory Models

Integrated constraint-based metabolic and regulatory models can accurately predict cellular growth phenotypes arising from genetic and environmental perturbations. Challenges in constructing such models involve the limited availability of information about transcription factor—gene target interactio...

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Detalles Bibliográficos
Autores principales: Barua, Dipak, Kim, Joonhoon, Reed, Jennifer L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965739/
https://www.ncbi.nlm.nih.gov/pubmed/21060853
http://dx.doi.org/10.1371/journal.pcbi.1000970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965739/
https://www.ncbi.nlm.nih.gov/pubmed/21060853
http://dx.doi.org/10.1371/journal.pcbi.1000970

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