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The De Novo Cytosine Methyltransferase DRM2 Requires Intact UBA Domains and a Catalytically Mutated Paralog DRM3 during RNA–Directed DNA Methylation in Arabidopsis thaliana

Eukaryotic DNA cytosine methylation can be used to transcriptionally silence repetitive sequences, including transposons and retroviruses. This silencing is stable between cell generations as cytosine methylation is maintained epigenetically through DNA replication. The Arabidopsis thaliana Dnmt3 cy...

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Detalles Bibliográficos
Autores principales: Henderson, Ian R., Deleris, Angelique, Wong, William, Zhong, Xuehua, Chin, Hang Gyeong, Horwitz, Gregory A., Kelly, Krystyna A., Pradhan, Sriharsa, Jacobsen, Steven E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965745/
https://www.ncbi.nlm.nih.gov/pubmed/21060858
http://dx.doi.org/10.1371/journal.pgen.1001182