DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes

Histone deacetylase Rpd3 is part of two distinct complexes: the large (Rpd3L) and small (Rpd3S) complexes. While Rpd3L targets specific promoters for gene repression, Rpd3S is recruited to ORFs to deacetylate histones in the wake of RNA polymerase II, to prevent cryptic initiation within genes. Meth...

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Detalles Bibliográficos
Autores principales: Drouin, Simon, Laramée, Louise, Jacques, Pierre-Étienne, Forest, Audrey, Bergeron, Maxime, Robert, François
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965751/
https://www.ncbi.nlm.nih.gov/pubmed/21060864
http://dx.doi.org/10.1371/journal.pgen.1001173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965751/
https://www.ncbi.nlm.nih.gov/pubmed/21060864
http://dx.doi.org/10.1371/journal.pgen.1001173

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