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Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype

Methylation of specific lysine residues in core histone proteins is essential for embryonic development and can impart active and inactive epigenetic marks on chromatin domains. The ubiquitous nuclear protein PTIP is encoded by the Paxip1 gene and is an essential component of a histone H3 lysine 4 (...

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Detalles Bibliográficos
Autores principales: Lefevre, Gaelle M., Patel, Sanjeevkumar R., Kim, Doyeob, Tessarollo, Lino, Dressler, Gregory R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965754/
https://www.ncbi.nlm.nih.gov/pubmed/21060806
http://dx.doi.org/10.1371/journal.pgen.1001142