Cargando…
Facioscapulohumeral Dystrophy: Incomplete Suppression of a Retrotransposed Gene
Each unit of the D4Z4 macrosatellite repeat contains a retrotransposed gene encoding the DUX4 double-homeobox transcription factor. Facioscapulohumeral dystrophy (FSHD) is caused by deletion of a subset of the D4Z4 units in the subtelomeric region of chromosome 4. Although it has been reported that...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965761/ https://www.ncbi.nlm.nih.gov/pubmed/21060811 http://dx.doi.org/10.1371/journal.pgen.1001181 |