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Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases

BACKGROUND: The WASF3 protein is involved in cell movement and invasion, and to investigate its role in prostate cancer progression we studied the phenotypic effects of knockdown in primary tumors and cell lines. METHODS: ShRNA was used to knockdown WASF3 function in prostate cell lines. Cell motili...

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Detalles Bibliográficos
Autores principales: Teng, Y, Ren, M Q, Cheney, R, Sharma, S, Cowell, J K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965863/
https://www.ncbi.nlm.nih.gov/pubmed/20717117
http://dx.doi.org/10.1038/sj.bjc.6605850