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Safety and Immunogenicity Following Administration of a Live, Attenuated Monovalent 2009 H1N1 Influenza Vaccine to Children and Adults in Two Randomized Controlled Trials

BACKGROUND: The safety, tolerability, and immunogenicity of a monovalent intranasal 2009 A/H1N1 live attenuated influenza vaccine (LAIV) were evaluated in children and adults. METHODS/PRINCIPAL FINDINGS: Two randomized, double-blind, placebo-controlled studies were completed in children (2–17 y) and...

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Detalles Bibliográficos
Autores principales: Mallory, Raburn M., Malkin, Elissa, Ambrose, Christopher S., Bellamy, Terramika, Shi, Li, Yi, Tingting, Jones, Taff, Kemble, George, Dubovsky, Filip
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966412/
https://www.ncbi.nlm.nih.gov/pubmed/21060780
http://dx.doi.org/10.1371/journal.pone.0013755