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Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine

BACKGROUND: Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial mechanism that involves inhibition of cell division. Berberine is a DNA ligand and may induce filamentation th...

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Detalles Bibliográficos
Autores principales: Boberek, Jaroslaw M., Stach, Jem, Good, Liam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966414/
https://www.ncbi.nlm.nih.gov/pubmed/21060782
http://dx.doi.org/10.1371/journal.pone.0013745