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Epitope Density Influences CD8(+) Memory T Cell Differentiation

BACKGROUND: The generation of long-lived memory T cells is critical for successful vaccination but the factors controlling their differentiation are still poorly defined. We tested the hypothesis that the strength of T cell receptor (TCR) signaling contributed to memory CD8(+) T cell generation. MET...

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Detalles Bibliográficos
Autores principales: Leignadier, Julie, Labrecque, Nathalie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966420/
https://www.ncbi.nlm.nih.gov/pubmed/21060788
http://dx.doi.org/10.1371/journal.pone.0013740