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Epitope Density Influences CD8(+) Memory T Cell Differentiation
BACKGROUND: The generation of long-lived memory T cells is critical for successful vaccination but the factors controlling their differentiation are still poorly defined. We tested the hypothesis that the strength of T cell receptor (TCR) signaling contributed to memory CD8(+) T cell generation. MET...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966420/ https://www.ncbi.nlm.nih.gov/pubmed/21060788 http://dx.doi.org/10.1371/journal.pone.0013740 |