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Common Variants of TLR1 Associate with Organ Dysfunction and Sustained Pro-Inflammatory Responses during Sepsis

BACKGROUND: Toll-like receptors (TLRs) are critical components for host pathogen recognition and variants in genes participating in this response influence susceptibility to infections. Recently, TLR1 gene polymorphisms have been found correlated with whole blood hyper-inflammatory responses to path...

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Detalles Bibliográficos
Autores principales: Pino-Yanes, Maria, Corrales, Almudena, Casula, Milena, Blanco, Jesús, Muriel, Arturo, Espinosa, Elena, García-Bello, Miguel, Torres, Antoni, Ferrer, Miguel, Zavala, Elizabeth, Villar, Jesús, Flores, Carlos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966434/
https://www.ncbi.nlm.nih.gov/pubmed/21048935
http://dx.doi.org/10.1371/journal.pone.0013759