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Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents

Background There is increasing evidence for genetic effects on the hypothalamic–pituitary axis system. More than one gene is likely to moderate corticoid-mediated activity. Aims To investigate whether the brain-derived neurotrophic factor (BDNF) polymorphism (rs6265, Val66Met) is associated with mor...

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Detalles Bibliográficos
Autores principales: Goodyer, Ian M., Croudace, Tim, Dudbridge, Frank, Ban, Maria, Herbert, Joe
Formato: Texto
Lenguaje:English
Publicado: Royal College Of Psychiatrists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966502/
https://www.ncbi.nlm.nih.gov/pubmed/21037213
http://dx.doi.org/10.1192/bjp.bp.110.077750