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Wnt signalling in adenomas of familial adenomatous polyposis patients

BACKGROUND: Epigenetic silencing of Wnt antagonists and expression changes in genes associated with Wnt response pathways occur in early sporadic colorectal tumourigenesis, indicating that tumour cells are more sensitive to Wnt growth factors and respond differently. In this study, we have investiga...

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Detalles Bibliográficos
Autores principales: Caldwell, G M, Jones, C E, Ashley, A M, Wei, W, Hejmadi, R K, Morton, D G, Matthews, G M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966613/
https://www.ncbi.nlm.nih.gov/pubmed/20628379
http://dx.doi.org/10.1038/sj.bjc.6605790