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Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats

The present study attempted to clarify whether over-secretion of glucocorticoids in the serum caused by increased hypothalamus-pituitary-adrenal activity induces oxidative stress in the rat brain, and how the stress causes the emergence of cognitive deficits. When rats were subcutaneously injected w...

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Detalles Bibliográficos
Autores principales: Sato, Hiroya, Takahashi, Takeyuki, Sumitani, Kazumi, Takatsu, Hirokatsu, Urano, Shiro
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966932/
https://www.ncbi.nlm.nih.gov/pubmed/21103031
http://dx.doi.org/10.3164/jcbn.10-58