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Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats
The present study attempted to clarify whether over-secretion of glucocorticoids in the serum caused by increased hypothalamus-pituitary-adrenal activity induces oxidative stress in the rat brain, and how the stress causes the emergence of cognitive deficits. When rats were subcutaneously injected w...
Autores principales: | Sato, Hiroya, Takahashi, Takeyuki, Sumitani, Kazumi, Takatsu, Hirokatsu, Urano, Shiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966932/ https://www.ncbi.nlm.nih.gov/pubmed/21103031 http://dx.doi.org/10.3164/jcbn.10-58 |
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