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Scavenging Effects of Dexrazoxane on Free Radicals
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron,...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
the Society for Free Radical Research Japan
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966934/ https://www.ncbi.nlm.nih.gov/pubmed/21103033 http://dx.doi.org/10.3164/jcbn.10-64 |