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Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements

The multicopy λgt10-lacZ transgene shuttle vector of Muta™Mouse serves as an important tool for genotoxicity studies. Here, we describe a model for λgt10-lacZ transgene molecular structure, based on characterisation of transgenes recovered from animals of our intramural breeding colony. Unique nucle...

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Detalles Bibliográficos
Autores principales: Shwed, Philip S., Crosthwait, Jennifer, Douglas, George R., Seligy, Vern L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966988/
https://www.ncbi.nlm.nih.gov/pubmed/20724577
http://dx.doi.org/10.1093/mutage/geq048