Exendin-4 Protects Oxidative Stress-Induced β-Cell Apoptosis through Reduced JNK and GSK3β Activity

Oxidative stress induced by chronic hyperglycemia in type 2 diabetes plays a crucial role in progressive loss of β-cell mass through β-cell apoptosis. Glucagon like peptide-1 (GLP-1) has effects on preservation of β-cell mass and its insulin secretory function. GLP-1 possibly increases islet cell ma...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Young, Lim, Dong-Mee, Moon, Chan Il, Jo, Kyung-Jin, Lee, Seong-Kyu, Baik, Haing-Woon, Lee, Ki-Ho, Lee, Kang-Woo, Park, Keun-Young, Kim, Byung-Joon
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967000/
https://www.ncbi.nlm.nih.gov/pubmed/21060752
http://dx.doi.org/10.3346/jkms.2010.25.11.1626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967000/
https://www.ncbi.nlm.nih.gov/pubmed/21060752
http://dx.doi.org/10.3346/jkms.2010.25.11.1626

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