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EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2

BAKGROUND: The EVI1(ecotropic virus integration site 1) gene codes for a zinc-finger transcription factor, whose transcriptional activation leads to a particularly aggressive form of acute myeloid leukaemia (AML). Although, EVI1 interactions with key proteins in hematopoiesis have been previously de...

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Detalles Bibliográficos
Autores principales: Gómez-Benito, M, Conchillo, A, García, M A, Vázquez, I, Maicas, M, Vicente, C, Cristobal, I, Marcotegui, N, García-Ortí, L, Bandrés, E, Calasanz, M J, Alonso, M M, Odero, M D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967053/
https://www.ncbi.nlm.nih.gov/pubmed/20842122
http://dx.doi.org/10.1038/sj.bjc.6605874