Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways

BACKGROUND: Wilms' tumour 1 (WT1) gene was discovered as a tumour suppressor gene. Later findings have suggested that WT1 also can be oncogenic. This complexity is partly explained by the fact that WT1 has a number of target genes. METHOD: WT1 and its target gene human telomerase reverse transc...

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Detalles Bibliográficos
Autores principales: Sitaram, R T, Degerman, S, Ljungberg, B, Andersson, E, Oji, Y, Sugiyama, H, Roos, G, Li, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967054/
https://www.ncbi.nlm.nih.gov/pubmed/20842112
http://dx.doi.org/10.1038/sj.bjc.6605878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967054/
https://www.ncbi.nlm.nih.gov/pubmed/20842112
http://dx.doi.org/10.1038/sj.bjc.6605878

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