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Mechanism of genotoxicity induced by targeted cytoplasmic irradiation

BACKGROUND: Direct damage to DNA is generally accepted as the main initiator of mutation and cancer induced by environmental carcinogens or ionising radiation. However, there is accumulating evidence suggesting that extracellular/extranuclear targets may also have a key role in mediating the genotox...

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Detalles Bibliográficos
Autores principales: Hong, M, Xu, A, Zhou, H, Wu, L, Randers-Pehrson, G, Santella, R M, Yu, Z, Hei, T K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967061/
https://www.ncbi.nlm.nih.gov/pubmed/20842121
http://dx.doi.org/10.1038/sj.bjc.6605888