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Mechanism of genotoxicity induced by targeted cytoplasmic irradiation
BACKGROUND: Direct damage to DNA is generally accepted as the main initiator of mutation and cancer induced by environmental carcinogens or ionising radiation. However, there is accumulating evidence suggesting that extracellular/extranuclear targets may also have a key role in mediating the genotox...
Autores principales: | Hong, M, Xu, A, Zhou, H, Wu, L, Randers-Pehrson, G, Santella, R M, Yu, Z, Hei, T K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967061/ https://www.ncbi.nlm.nih.gov/pubmed/20842121 http://dx.doi.org/10.1038/sj.bjc.6605888 |
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