Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia

INTRODUCTION: Autophagy enables cells to recycle long-lived proteins or damaged organelles. Beclin 1, the mammalian orthologue of the yeast Apg6/Vps30 gene, functions as a scaffold for the formation of autophagosomes. MATERIALS AND METHOD: The immunohistochemical patterns of Beclin 1 expression and...

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Detalles Bibliográficos
Autores principales: Koukourakis, M I, Giatromanolaki, A, Sivridis, E, Pitiakoudis, M, Gatter, K C, Harris, A L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967071/
https://www.ncbi.nlm.nih.gov/pubmed/20842118
http://dx.doi.org/10.1038/sj.bjc.6605904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967071/
https://www.ncbi.nlm.nih.gov/pubmed/20842118
http://dx.doi.org/10.1038/sj.bjc.6605904

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