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MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status

BACKGROUND: Esophageal adenocarcinomas (EACs) arise due to gastroesophageal reflux, with Barrett's esophagus (BE) regarded as precancerous lesion. Matrix metalloproteinases (MMPs) might play a role during the multistep carcinogenetic process. METHODS: Expression of MMP-1 and -13 was analyzed in...

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Detalles Bibliográficos
Autores principales: Grimm, Martin, Lazariotou, Maria, Kircher, Stefan, Stuermer, Luisa, Reiber, Christoph, Höfelmayr, Andreas, Gattenlöhner, Stefan, Otto, Christoph, Germer, Christoph T, von Rahden, Burkhard HA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967517/
https://www.ncbi.nlm.nih.gov/pubmed/20946664
http://dx.doi.org/10.1186/1479-5876-8-99