The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis

BACKGROUND: Among the most harmful of all genetic abnormalities that appear in colorectal cancer (CRC) development are mutations of KRAS and its downstream effector BRAF as they result in abnormal extracellular signal-related kinase (ERK) signaling. In a previous report, we had shown that expression...

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Detalles Bibliográficos
Autores principales: Bergeron, Sébastien, Lemieux, Etienne, Durand, Véronique, Cagnol, Sébastien, Carrier, Julie C, Lussier, Jacques G, Boucher, Marie-Josée, Rivard, Nathalie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967542/
https://www.ncbi.nlm.nih.gov/pubmed/20942929
http://dx.doi.org/10.1186/1476-4598-9-271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967542/
https://www.ncbi.nlm.nih.gov/pubmed/20942929
http://dx.doi.org/10.1186/1476-4598-9-271

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