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Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia

BACKGROUND: Preclinical studies demonstrated that small chain RNA fragments accelerate the recovery of platelets numbers in animals exposed to high doses of chemotherapeutic drugs. There is anecdotal data supporting the same application in humans. The Phase I clinical trial described here was design...

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Detalles Bibliográficos
Autores principales: Levin, Robert D, Daehler, MaryAnn, Grutsch, James F, Hall, John L, Gupta, Digant, Lis, Christopher G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967549/
https://www.ncbi.nlm.nih.gov/pubmed/20955619
http://dx.doi.org/10.1186/1471-2407-10-565