Cargando…

Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia

BACKGROUND: Preclinical studies demonstrated that small chain RNA fragments accelerate the recovery of platelets numbers in animals exposed to high doses of chemotherapeutic drugs. There is anecdotal data supporting the same application in humans. The Phase I clinical trial described here was design...

Descripción completa

Detalles Bibliográficos
Autores principales:	Levin, Robert D, Daehler, MaryAnn, Grutsch, James F, Hall, John L, Gupta, Digant, Lis, Christopher G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967549/ https://www.ncbi.nlm.nih.gov/pubmed/20955619 http://dx.doi.org/10.1186/1471-2407-10-565

Ejemplares similares

Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer
por: Grutsch, James F, et al.
Publicado: (2011)

Distribution and determinants of patient satisfaction in oncology with a focus on health related quality of life
por: Lis, Christopher G, et al.
Publicado: (2009)

The association of quality of life with potentially remediable disruptions of circadian sleep/activity rhythms in patients with advanced lung cancer
por: Grutsch, James F, et al.
Publicado: (2011)

Prevalence, sources, and predictors of soy consumption in breast cancer
por: Lammersfeld, Carolyn A, et al.
Publicado: (2009)

Borderline Thrombocytopenia or Mild Idiopathic Thrombocytopenic Purpura?
por: Zimmer, Jacques, et al.
Publicado: (2006)

The relationship between bioelectrical impedance phase angle and subjective global assessment in advanced colorectal cancer
por: Gupta, Digant, et al.
Publicado: (2008)

Bioelectrical impedance phase angle as a prognostic indicator in breast cancer
por: Gupta, Digant, et al.
Publicado: (2008)

Bioelectrical impedance phase angle in clinical practice: implications for prognosis in stage IIIB and IV non-small cell lung cancer
por: Gupta, Digant, et al.
Publicado: (2009)

Detection and dynamics of anti‐platelet antibodies in thrombocytopenic dogs with and without idiopathic immune thrombocytopenia
por: Shropshire, Sarah, et al.
Publicado: (2020)

Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
por: Gupta, Digant, et al.
Publicado: (2009)

Pretreatment serum albumin as a predictor of cancer survival: A systematic review of the epidemiological literature
por: Gupta, Digant, et al.
Publicado: (2010)

Can changes in health related quality of life scores predict survival in stages III and IV colorectal cancer?
por: Braun, Donald P, et al.
Publicado: (2011)

Elasomeran/tozinameran: Thrombocytopenia and thrombocytopenic-purpura: 2 case reports
Publicado: (2022)

Individualized chemotherapy drug dose escalation in dogs with multicentric lymphoma
por: Siewert, Jacob M., et al.
Publicado: (2023)

The relationship between perceived service quality and patient willingness to recommend at a national oncology hospital network
por: Lis, Christopher G, et al.
Publicado: (2011)

Distribution and determinants of patient satisfaction in oncology: A review of the literature
por: Lis, Christopher G, et al.
Publicado: (2009)

Patient satisfaction with service quality in an oncology setting: implications for prognosis in non-small cell lung cancer
por: Gupta, Digant, et al.
Publicado: (2013)

The Relationship between Patient Satisfaction with Service Quality and Survival in Non-Small Cell Lung Cancer – Is Self-Rated Health a Potential Confounder?
por: Lis, Christopher G., et al.
Publicado: (2015)

Self-rated health supersedes patient satisfaction with service quality as a predictor of survival in prostate cancer
por: Gupta, Digant, et al.
Publicado: (2015)

5 Yearsʼ Experience of a Tertiary Center with Thrombocytopenic Pregnancies: Gestational Thrombocytopenia, Idiopathic Thrombocytopenic Purpura and Hypertensive Disorders of Pregnancy
por: Fadiloglu, Erdem, et al.
Publicado: (2020)

HIV associated thrombocytopenia, misdiagnosed as thrombotic thrombocytopenic purpura: a case report
por: Khorvash, Farzin, et al.
Publicado: (2009)

Can we predict neonatal thrombocytopenia in offspring of women with idiopathic thrombocytopenic purpura?
por: Hachisuga, Kazuhisa, et al.
Publicado: (2014)

Congenital Thrombotic Thrombocytopenic Purpura: A Rare Cause of Recurrent Thrombocytopenia and Anemia
por: Assiri, Mona, et al.
Publicado: (2023)

Definitive radiotherapy dose escalation with chemotherapy for treating non-metastatic oesophageal cancer
por: Fan, Chao-Yueh, et al.
Publicado: (2018)

Short-term dose-escalated romiplostim for preparing an adult patient with persistent newly diagnosed primary immune thrombocytopenia for splenectomy
por: Murray, Nigel P., et al.
Publicado: (2020)

The relationship between patient satisfaction with service quality and survival in pancreatic cancer
por: Gupta, Digant, et al.
Publicado: (2012)

Improvement of thrombocytopenia after treatment for Helicobacter pylori in a patient with immunologic thrombocytopenic purpura
por: Rocha, Aline Maia, et al.
Publicado: (2014)

Thrombocytopenia with absent radii syndrome with delayed presentation of thrombocytopenic episodes: a case report
por: Alassri, Riffa, et al.
Publicado: (2023)

PB2261: LINEZOLID AS A SAFE ANTIMICROBIAL AGENT IN THROMBOCYTOPENIC PATIENTS UNDERGOING CHEMOTHERAPY FOR HEMATOLOGIC MALIGNANCIES
por: Angotzi, F., et al.
Publicado: (2022)

Subclinical cardiotoxicity following adjuvant dose-escalated FEC, high-dose chemotherapy, or CMF in breast cancer
por: Erselcan, T, et al.
Publicado: (2000)

Efficiency of New Dose Escalation Designs in Dose-Finding Phase I Trials of Molecularly Targeted Agents
por: Le Tourneau, Christophe, et al.
Publicado: (2012)

Dose escalation of a curcuminoid formulation
por: Lao, Christopher D, et al.
Publicado: (2006)

Assessment and impact of dose escalation on anti-drug antibodies in Fabry disease
por: Lenders, Malte, et al.
Publicado: (2022)

Successful prevention of exacerbation of thrombocytopenia in a pregnant patient with idiopathic thrombocytopenic purpura by anticoagulation treatment
por: Hisano, Michi, et al.
Publicado: (2015)

A Novel Use of Tisseel in the Setting of Uncontrolled Bleeding in a Thrombocytopenic Patient With Idiopathic Thrombocytopenia
por: Fisher, John S., et al.
Publicado: (2015)

Thrombotic thrombocytopenic purpura presenting as recurrent thrombocytopenia in a young female — A case report
por: Shanmugam, Sri Gayathri, et al.
Publicado: (2020)

Patient perspectives on chemotherapy de‐escalation in breast cancer
por: Rocque, Gabrielle B., et al.
Publicado: (2021)

Dose escalation of radiation therapy with or without induction chemotherapy for unresectable locally advanced pancreatic cancer
por: Ma, Sung Jun, et al.
Publicado: (2018)

IMMUNOREACTIONS INVOLVING PLATELETS : IV. STUDIES ON THE PATHOGENESIS OF THROMBOCYTOPENIA IN DRUG PURPURA USING TEST DOSES OF QUINIDINE IN SENSITIZED INDIVIDUALS; THEIR IMPLICATIONS IN IDIOPATHIC THROMBOCYTOPENIC PURPURA
por: Shulman, N. Raphael
Publicado: (1958)

A Case of Refractory Thrombocytopenia with 5q Deletion: Myelodysplastic Syndrome Mimicking Idiopathic Thrombocytopenic Purpura
por: Chang, Jeonghyun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7rpvcfkc1qq0gg2rdpdphlifqh