Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females

It is well known that thyroid disease is more frequent in women than in men, however the molecular basis for this gender difference is still poorly understood. PI3K activation, through different mechanisms including loss of the PTEN tumor suppressor, is being increasingly recognized as a major playe...

Descripción completa

Detalles Bibliográficos
Autores principales: Arciuch, Valeria Gabriela Antico, Dima, Mariavittoria, Liao, Xiao-Hui, Refetoff, Samuel, Di Cristofano, Antonio
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967724/
https://www.ncbi.nlm.nih.gov/pubmed/20676139
http://dx.doi.org/10.1038/onc.2010.308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967724/
https://www.ncbi.nlm.nih.gov/pubmed/20676139
http://dx.doi.org/10.1038/onc.2010.308

Ejemplares similares