Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling

We introduce quantitative dynamic footprinting microscopy to resolve neutrophil rolling on P-selectin. We show that the footprint of a rolling neutrophil is four times larger than previously thought, the P-selectin-PSGL-1 bonds are relaxed at the leading edge of the rolling cell, compressed under th...

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Detalles Bibliográficos
Autores principales: Sundd, Prithu, Gutierrez, Edgar, Pospieszalska, Maria K., Zhang, Hong, Groisman, Alexander, Ley, Klaus
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967732/
https://www.ncbi.nlm.nih.gov/pubmed/20871617
http://dx.doi.org/10.1038/nmeth.1508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967732/
https://www.ncbi.nlm.nih.gov/pubmed/20871617
http://dx.doi.org/10.1038/nmeth.1508

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