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Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models
BACKGROUND: Mouse xenograft models, in which human cancer cells are implanted in immune-suppressed mice, have been popular for studying the mechanisms of novel therapeutic targets, tumor progression and metastasis. We hypothesized that we could exploit the interspecies genetic differences in these e...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967741/ https://www.ncbi.nlm.nih.gov/pubmed/21044358 http://dx.doi.org/10.1186/1471-2105-11-S9-S11 |