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Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models

BACKGROUND: Mouse xenograft models, in which human cancer cells are implanted in immune-suppressed mice, have been popular for studying the mechanisms of novel therapeutic targets, tumor progression and metastasis. We hypothesized that we could exploit the interspecies genetic differences in these e...

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Detalles Bibliográficos
Autores principales: Yang, Xinan, Lee, Younghee, Huang, Yong, Chen, James L, Xing, Rosie H, Lussier, Yves A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967741/
https://www.ncbi.nlm.nih.gov/pubmed/21044358
http://dx.doi.org/10.1186/1471-2105-11-S9-S11