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Assessment of genetic variation for the LINE-1 retrotransposon from next generation sequence data
BACKGROUND: In humans, copies of the Long Interspersed Nuclear Element 1 (LINE-1) retrotransposon comprise 21% of the reference genome, and have been shown to modulate expression and produce novel splice isoforms of transcripts from genes that span or neighbor the LINE-1 insertion site. RESULTS: In...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967742/ https://www.ncbi.nlm.nih.gov/pubmed/21044359 http://dx.doi.org/10.1186/1471-2105-11-S9-S12 |