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An integrative method for scoring candidate genes from association studies: application to warfarin dosing

BACKGROUND: A key challenge in pharmacogenomics is the identification of genes whose variants contribute to drug response phenotypes, which can include severe adverse effects. Pharmacogenomics GWAS attempt to elucidate genotypes predictive of drug response. However, the size of these studies has sev...

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Detalles Bibliográficos
Autores principales: Tatonetti, Nicholas P, Dudley, Joel T, Sagreiya, Hersh, Butte, Atul J, Altman, Russ B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967750/
https://www.ncbi.nlm.nih.gov/pubmed/21044367
http://dx.doi.org/10.1186/1471-2105-11-S9-S9