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An integrative method for scoring candidate genes from association studies: application to warfarin dosing
BACKGROUND: A key challenge in pharmacogenomics is the identification of genes whose variants contribute to drug response phenotypes, which can include severe adverse effects. Pharmacogenomics GWAS attempt to elucidate genotypes predictive of drug response. However, the size of these studies has sev...
Autores principales: | Tatonetti, Nicholas P, Dudley, Joel T, Sagreiya, Hersh, Butte, Atul J, Altman, Russ B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967750/ https://www.ncbi.nlm.nih.gov/pubmed/21044367 http://dx.doi.org/10.1186/1471-2105-11-S9-S9 |
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