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Ethyl 4-{1-[(2,4-dinitro­phen­yl)hydrazono]eth­yl}-5-(2-naphthyl­methoxy­meth­yl)isoxazole-3-carboxyl­ate

The title compound, C(26)H(23)N(5)O(8), was prepared and its structure investigated to further develop a working hypothesis for the essential binding pharmacophore for ligands of the System Xc- transporter [Patel et al. (2004 ▶). Neuropharmacology, 46, 273–284]. The hydrazone group displays an E geo...

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Detalles Bibliográficos
Autores principales: Natale, Nicholas R., Szabon-Watola, Monica I., Twamley, Brendan, Bridges, Richard J., Patel, Sarjubhai, Rajale, Trideep
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968060/
https://www.ncbi.nlm.nih.gov/pubmed/21581603
http://dx.doi.org/10.1107/S1600536808041901